Mami Yamada, Ph.D
Assistant professor








Education
2016: B.S., Aichi Institute of Technology Department of Applied Chemistry
2018: M.S., Nagoya City University Graduate School of Natural Sciences
2021: Ph.D., Nagoya City University Graduate School of Natural Sciences

Research/Professional Experience
2017: Teaching Assistant, Nagoya City University
2017-current: Teaching Assistant, Outreach program for high school students, Nagoya City University
2018: Teaching Assistant, JSPS outreach program (Hirameki-Tokimeki Science)
2018-2021: Research Assistant, Graduate School of Natural Sciences Nagoya City University
2020-2021: Research Fellowship for Young Scientist from Japanese Society for the Promotion of Science (JSPS-DC2)
2021-2022: Research Fellowship for Young Scientist from Japanese Society for the Promotion of Science (JSPS-PD)
2021-2024: Research Fellowship, Graduate School of Science, Nagoya City University
2024-current: Assistant professor, Graduate School Science, Nagoya City University

Research/Discipline
Muscle Physiology and Biology, Molecular Physiology, Cell Biology

Publication
new 8. Himori K, Yamada M, Onoki T, Matsumaru D, Motohashi H, Okutsu M. Nrf2 deficiency in muscle attenuates experimental autoimmune myositis-induced muscle weakness. J Physiol. 602(22):6189-6207, 2024.
new 7. Yamada M, Warabi E, Oishi H, Lira VA, Okutsu M. Muscle-derived IL-1β regulates EcSOD expression via the NBR1-p62-Nrf2 pathway in muscle during cancer cachexia. J Physiol. 602(17):4215-4235, 2024.
6 Yamada M, Okutsu M. Interleukin-1β triggers muscle-derived extracellular superoxide dismutase expression and protects muscles from doxorubicin-induced atrophy. J Physiol. 601(21):4699-4721, 2023.
5. Yamada M, Warabi E, Oishi H, Lira VA, Okutsu M. Muscle p62 stimulates the expression of antioxidant proteins alleviating cancer cachexia. FASEB J. 37(9):e23156, 2023.
4. Okutsu M, Yamada M, Tokizawa K, Marui S, Suzuki K, Lira VA, Nagashima K. Regular exercise stimulates endothelium autophagy via IL-1 signaling in ApoE deficient mice. FASEB J. 35:e21698, 2021.
3. Yamada M, Hokazono C, Tokizawa K, Marui S, Iwata M, Lira VA, Suzuki K, Miura S, Nagashima K, Okutsu M. Muscle-derived SDF-1α/CXCL12 modulates endothelial cell proliferation but not exercise training-induced angiogenesis. Am J Physiol Regul Integr Comp Physiol. 317:R770-779, 2019.
2. Yamada M, Iwata M, Warabi E, Oishi H, Lira VA, Okutsu M. p62/SQSTM1 and Nrf2 are essential for exercise-mediated enhancement of antioxidant protein expression in oxidative muscle. FASEB J. 33:8022-8032, 2019.
1. Yamada M, Hokazono C, Okutsu M. Maternal exercise training attenuates endotoxin-induced sepsis in mice offspring. Biochem Biophys Rep. 15:19-24, 2018.

Award/Grant
new 2024: Aichi Health Promotion Foundation, Role: PI
new 2024-2025: JSPS, Grant-in-Aid for Young Scientists, Role: PI
new 2024: The Nippon Foundation, Role: PI
2022: The Uehara Memorial Foundation, Role: PI
2022-2023: JSPS, Grant-in-Aid for Young Scientists, Role: PI
2021: Suzuken Memorial Foundation, Role: PI
2021: The Descente and Ishimoto Memorial Foundation for the Promotion of Sports Science, Role: PI
2021: The Nakatomi Foundation, Role: PI
2020: Aichi Health Promotion Foundation, Role: PI
2019: The Japan Science Foundation, Role: PI
2018: Travel grant for International conference, Nagoya City University
2018: First Prize, Master thesis presentation, Graduate School of Natural Sciences, Nagoya City University
2017: Travel grant for International conference, Nagoya City University
2017: Encouraging Prize, Tokai Japanese Society of Physical Fitness and Sports Medicine Regional Chapter