名古屋市立大学大学院 理学研究科 総合生命理学部

Japanese English

名古屋市立大学大学院 理学研究科 総合生命理学部

Japanese English
Campus Map | Access | Contact Us

名古屋市立大学大学院 理学研究科 総合生命理学部

Japanese English

Faculty Members

Yoshiyuki SUZUKI

Division
Biological Science, Professor
Academic Degree
M.D., Ph.D.
Research FieldInformation Biology, Molecular Evolution, Population Genetics, Virology
Keywordsnatural selection, neutral evolution
Current Research Topics(1) Study of virus evolution:
Viruses are not included in the Tree of Life, which is composed of archaebacteria, eubacteria, and eukaryotes. When and how did viruses emerge? How did they evolve? What is the effective strategy for prophylaxis and treatment against diseases caused by rapidly evolving viruses? To solve these problems, we are studying molecular evolution of viruses.

(2) Development of methods for detecting natural selection:
Did evolution occur through accumulation of neutral or nearly neutral mutations or through accumulation of advantageous mutations? To solve this problem, we are analyzing biological data, such as genomic sequences, through developing methods for detecting natural selection.

(3) Evolutionary study of disease-associated genes:
Why do we age, get sick, and eventually die? Why are some organisms immortal, while others are not? To solve these problems, we will conduct evolutionary study of aging- and disease-associated genes using biological data, such as expression profiles and interaction networks.
Selected Publications

*Yoshiyuki Suzuki, Yen Hai Doan, Hirokazu Kimura, Hiroto Shinomiya, Komei Shirabe, Kazuhiko Katayama
Predicting genotype compositions in norovirus seasons in Japan.
Microbiology and Immunology, 2016, 60:418-426.

*Yoshiyuki Suzuki
Selecting vaccine strains for H3N2 human influenza A virus.
Meta Gene, 2015, 4:64-72.

*Yoshiyuki Suzuki
A possible packaging signal in the rotavirus genome.
Genes & Genetic Systems, 2014, 89:81-86.

Yuki Kobayashi, *Yoshiyuki Suzuki
Evidence for N-glycan shielding of antigenic sites during evolution of human influenza A virus hemagglutinin.
Journal of Virology, 2012, 86:3446-3451.

*Masatoshi Nei, Yoshiyuki Suzuki, Masafumi Nozawa
The neutral theory of molecular evolution in the genomic era.
Annual Review of Genomics and Human Genetics, 2010, 11:265-289.

*Yoshiyuki Suzuki
Natural selection on the influenza virus genome. 
Molecular Biology and Evolution, 2006, 23:1902-1911.

*Yoshiyuki Suzuki, Masatoshi Nei
Origin and evolution of influenza virus hemagglutinin genes. 
Molecular Biology and Evolution, 2002, 19:501-509.

Yoshiyuki Suzuki, Galina V. Glazko, *Masatoshi Nei
Overcredibility of molecular phylogenies obtained by Bayesian phylogenetics.
Proceedings of the National Academy of Sciences of the United States of America, 2002, 99:16138-16143.

Yoshiyuki Suzuki, *Takashi Gojobori
A method for detecting positive selection at single amino acid sites. 
Molecular Biology and Evolution, 1999, 16:1315-1328.

Yoshiyuki Suzuki, *Takashi Gojobori
The origin and evolution of Ebola and Marburg viruses.
Molecular Biology and Evolution, 1997, 14:800-806.

Yoshiyuki Suzuki, Takeshi Sanekata, Mitsuo Sato, Kazuhiko Tajima, Yukihisa Matsuda, *Osamu Nakagomi
Relative frequencies of G (VP7) and P (VP4) serotypes determined by polymerase chain reaction assays among Japanese bovine rotaviruses isolated in cell culture.
Journal of Clinical Microbiology, 1993, 31:3046-3049.